Pulse inversion chirp coded tissue harmonic imaging (PI-CTHI) of Zebrafish heart using high frame rate ultrasound biomicroscopy.

作者: Jinhyoung Park , Ying Huang , Ruimin Chen , Jungwoo Lee , Thomas M. Cummins

DOI: 10.1007/S10439-012-0636-Y

关键词:

摘要: This paper reports a pulse inversion chirp coded tissue harmonic imaging (PI-CTHI) method for visualizing small animal hearts that provides fine spatial resolution at high frame rate without sacrificing the echo signal to noise ratio (eSNR). A 40 MHz lithium niobate (LiNbO3) single element transducer is employed evaluate performance of PI-CTHI by scanning tungsten wire targets, spherical anechoic voids, and zebrafish hearts. The phantom results show improves eSNR 4 dB from conventional (PI-THI), while still maintaining 88 110 μm in axial lateral directions, respectively. range side lobe level 11 lower than band-pass filtered CTHI (or F-CTHI). In sphere study, contrast-to-noise found be 2.7, indicating 34% enhancement over PI-THI. Due such improved contrast resolution, blood clots can readily visualized throughout heart regeneration after 20% ventricle removed. Disappearance early stages has been observed 7 days fish.

参考文章(21)
Fabian Kiessling, Bernd J. Pichler, Small animal imaging : basics and practical guide Springer. ,(2011)
Richard S. C. Cobbold, Roozbeh Arshadi, Alfred C. H. Yu, CODED EXCITATION METHODS FOR ULTRASOUND HARMONIC IMAGING Canadian Acoustics. ,vol. 35, pp. 35- 46 ,(2007)
Christian Hohl, Thorsten Schmidt, Patrick Haage, Dagmar Honnef, Marcus Blaum, Gundula Staatz, Rolf W. Guenther, Phase-inversion tissue harmonic imaging compared with conventional B-mode ultrasound in the evaluation of pancreatic lesions. European Radiology. ,vol. 14, pp. 1109- 1117 ,(2004) , 10.1007/S00330-003-2191-2
Martijn E. Frijlink, David E. Goertz, Ayache Bouakaz, Antonius F. W. van der Steen, A simulation study on tissue harmonic imaging with a single-element intravascular ultrasound catheter. Journal of the Acoustical Society of America. ,vol. 120, pp. 1723- 1731 ,(2006) , 10.1121/1.2226069
R.Y. Chiao, Xiaohui Hao, Coded excitation for diagnostic ultrasound: a system developer's perspective ieee symposium on ultrasonics. ,vol. 52, pp. 160- 170 ,(2003) , 10.1109/TUFFC.2005.1406543
Chris Jopling, Eduard Sleep, Marina Raya, Mercè Martí, Angel Raya, Juan Carlos Izpisúa Belmonte, Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation Nature. ,vol. 464, pp. 606- 609 ,(2010) , 10.1038/NATURE08899
Emmanuel W Cherin, Jens Kristian Poulsen, A.F.W van der Steen, Paul Lum, F.Stuart Foster, Experimental characterization of fundamental and second harmonic beams for a high-frequency ultrasound transducer Ultrasound in Medicine and Biology. ,vol. 28, pp. 635- 646 ,(2002) , 10.1016/S0301-5629(02)00498-2
Jaehee Song, Sangwon Kim, Hak-yeol Sohn, Tai-kyong Song, Yang Mo Yoo, Coded excitation for ultrasound tissue harmonic imaging. Ultrasonics. ,vol. 50, pp. 613- 619 ,(2010) , 10.1016/J.ULTRAS.2010.01.001
M. Pauliina Ramo, Timothy Spencer, Peter P. Kearney, Stuart T.R.D. Shaw, Ian R. Starkey, W. Norman McDicken, Keith A.A. Fox, CHARACTERISATION OF RED AND WHITE THROMBUS BY INTRAVASCULAR ULTRASOUND USING RADIOFREQUENCY AND VIDEODENSITOMETRIC DATA-BASED TEXTURE ANALYSIS Ultrasound in Medicine and Biology. ,vol. 23, pp. 1195- 1199 ,(1997) , 10.1016/S0301-5629(97)00118-X
Eric Johnstone, Stephan E. Friedl, Alok Maheshwari, George S. Abela, Distinguishing characteristics of erythrocyte-rich and platelet-rich thrombus by intravascular ultrasound catheter system. Journal of Thrombosis and Thrombolysis. ,vol. 24, pp. 233- 239 ,(2007) , 10.1007/S11239-007-0027-7