作者: Jinhyoung Park , Ying Huang , Ruimin Chen , Jungwoo Lee , Thomas M. Cummins
DOI: 10.1007/S10439-012-0636-Y
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摘要: This paper reports a pulse inversion chirp coded tissue harmonic imaging (PI-CTHI) method for visualizing small animal hearts that provides fine spatial resolution at high frame rate without sacrificing the echo signal to noise ratio (eSNR). A 40 MHz lithium niobate (LiNbO3) single element transducer is employed evaluate performance of PI-CTHI by scanning tungsten wire targets, spherical anechoic voids, and zebrafish hearts. The phantom results show improves eSNR 4 dB from conventional (PI-THI), while still maintaining 88 110 μm in axial lateral directions, respectively. range side lobe level 11 lower than band-pass filtered CTHI (or F-CTHI). In sphere study, contrast-to-noise found be 2.7, indicating 34% enhancement over PI-THI. Due such improved contrast resolution, blood clots can readily visualized throughout heart regeneration after 20% ventricle removed. Disappearance early stages has been observed 7 days fish.