Drug-Induced Liver Injury: The Role of Drug Metabolism and Transport
作者： Alberto Corsini , Michele Bortolini
DOI: 10.1002/JCPH.23
关键词:
摘要: … CYP3A4 has the highest abundance of all CYP450 enzymes in the human liver, although its expression … Metabolic enzymes involved in Phase II reactions include uridine diphosphate …
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E. H. Liu, C-N. Lee, Y-C. Lin, M-C. Yu, K-J. Bai, H-Y. Chen, J-C. Chang, UGT1A1 polymorphisms associated with risk of induced liver disorders by anti-tuberculosis medications. International Journal of Tuberculosis and Lung Disease. ,vol. 16, pp. 376- 378 ,(2012) , 10.5588/IJTLD.11.0404
Neil Kaplowitz, Drug-induced liver disorders: implications for drug development and regulation. Drug Safety. ,vol. 24, pp. 483- 490 ,(2001) , 10.2165/00002018-200124070-00001
Zhan S, Sun F, Chen Y, Xiang Y, Drug-metabolising enzyme polymorphisms and predisposition to anti-tuberculosis drug-induced liver injury: a meta-analysis. International Journal of Tuberculosis and Lung Disease. ,vol. 12, pp. 994- 1002 ,(2008)
SW Lee, L Chung, HH Huang, TY Chuang, YH Liou, L Wu, NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis. International Journal of Tuberculosis and Lung Disease. ,vol. 14, pp. 622- 626 ,(2010)
Agnés Poirier, Thierry Lavé, Johannes Noé, Christoph Funk, New strategies to address drug-drug interactions involving OATPs. Current Opinion in Drug Discovery & Development. ,vol. 10, pp. 74- 83 ,(2007)
Andreas Limmer, Jutta Ohl, Christian Kurts, Hans-Gustaf Ljunggren, Yuval Reiss, Marcus Groettrup, Frank Momburg, Bernd Arnold, Percy A. Knolle, Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance. Nature Medicine. ,vol. 6, pp. 1348- 1354 ,(2000) , 10.1038/82161
T Aoyama, S Yamano, D J Waxman, D P Lapenson, U A Meyer, V Fischer, R Tyndale, T Inaba, W Kalow, H V Gelboin, F J Gonzalez, Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine. Journal of Biological Chemistry. ,vol. 264, pp. 10388- 10395 ,(1989) , 10.1016/S0021-9258(18)81632-5
S. Chatterjee, N. Lyle, A. Mandal, S. Kundu, GSTT1 and GSTM1 gene deletions are not associated with hepatotoxicity caused by antitubercular drugs. Journal of Clinical Pharmacy and Therapeutics. ,vol. 35, pp. 465- 470 ,(2010) , 10.1111/J.1365-2710.2009.01101.X
Hansruedi Glatt, Sulfation and sulfotransferases 4: bioactivation of mutagens via sulfation. The FASEB Journal. ,vol. 11, pp. 314- 321 ,(1997) , 10.1096/FASEBJ.11.5.9141497
SLCO1B1 variants and statin-induced myopathy--a genomewide study The New England Journal of Medicine. ,vol. 359, pp. 789- 799 ,(2008) , 10.1056/NEJMOA0801936