N-terminal acetylation in paenibacillin, a novel lantibiotic

作者: Zengguo He , Chunhua Yuan , Liwen Zhang , Ahmed E. Yousef

DOI: 10.1016/J.FEBSLET.2008.07.008

关键词:

摘要: N-terminal acetylation was uncovered in paenibacillin, a novel lantibiotic recently reported as product of Paenibacillus polymyxa OSY-DF. This modification is unprecedented among bacteria-derived antimicrobial peptides and further illustrates the broad range modifications that can occur lantibiotics. Additionally, primary structure paenibacillin has been finally determined unequivocally by extensive NMR analysis taken together with previous MS/MS results. These analyses revealed one most post-translationally modified

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