Induction of antigen specific immunologic tolerance

摘要: Antigen specific immune tolerance is induced in a mammalian host by administration of toleragen combination with regimen immunosuppression. The methods optionally include preceding conditioning period, where immunosuppressive agents are administered the absence toleragen. After tolerizing regimen, withdrawn from suppressive agents, but able to maintain immunogenic epitopes present on Optimally, will have high uptake properties that allow vivo at low concentrations wide variety cell types.