Vasodilator therapy in clinical sepsis with low output syndrome

作者: Frank B. Cerra , James Hassett , John H. Siegel

DOI: 10.1016/0022-4804(78)90074-4

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摘要: Abstract Eight patients presented with gram-negative speticemia and septic shock. After appropriate medical surgical therapy, they underwent a transition from high cardiac output, low TPR state into cardiac, significant fall in oxygen consumption. This was refractory to maximized volume expansion inotropic support. Vasodilator therapy nitroglycerine paste initiated along intense, longitudinal physiologic assessment. All had TPR, rise improvement contractility, increase Five of the eight survived. is an effective mode treating often catastrophic complication myocardial decompensation

参考文章(8)
John H. Siegel, John H. Siegel, Herman P. Friedman, Herman P. Friedman, Roger M. Goldwyn, Roger M. Goldwyn, Pattern and process in the evolution of human septic shock. Surgery. ,vol. 70, pp. 232- 245 ,(1971) , 10.5555/URI:PII:0039606071901814
René Wégria, John L. Nickerson, Robert B. Case, James F. Holland, Effect of nitroglycerine on the cardiovascular system of normal persons The American Journal of Medicine. ,vol. 10, pp. 414- 418 ,(1951) , 10.1016/0002-9343(51)90286-0
M. IRENÉ FERRER, STANLEY E. BRADLEY, HENRY O. WHEELER, YALE ENSON, RUDOLPH PREISIG, PHILIP W. BRICKNER, RICHARD J. CONROY, RÉJANE M. HARVEY, Some Effects of Nitroglycerin upon the Splanchnic, Pulmonary, and Systemic Circulations Circulation. ,vol. 33, pp. 357- 373 ,(1966) , 10.1161/01.CIR.33.3.357
L. BERNSTEIN, G. C. FRIESINGER, P. R. LICHTLEN, R. S. ROSS, The Effect of Nitroglycerin on the Systemic and Coronary Circulation in Man and Dogs Circulation. ,vol. 33, pp. 107- 116 ,(1966) , 10.1161/01.CIR.33.1.107
JOHN F. WILLIAMS, GERALD GLICK, EUGENE BRAUNWALD, Studies on cardiac dimensions in intact unanesthetized man. V. Effects of nitroglycerin. Circulation. ,vol. 32, pp. 767- 771 ,(1965) , 10.1161/01.CIR.32.5.767
George G. Rowe, Carl J. Chelius, Skoda Afonso, Hans P. Gurtner, Charles W. Crumpton, SYSTEMIC AND CORONARY HEMODYNAMIC EFFECTS OF ERYTHROL TETRANITRATE Journal of Clinical Investigation. ,vol. 40, pp. 1217- 1222 ,(1961) , 10.1172/JCI104352
D. C. Harrison, A. Goldblatt, E. Braunwald, G. Glick, D. T. Mason, Studies on Cardiac Dimensions in Intact, Unanesthetized Man Circulation Research. ,vol. 13, pp. 448- 467 ,(1963) , 10.1161/01.RES.13.5.448
James S. Forrester, Protasio L. da Luz, Kanu Chatterjee, Peripheral Vasodilators in Low Cardiac Output States Surgical Clinics of North America. ,vol. 55, pp. 531- 544 ,(1975) , 10.1016/S0039-6109(16)40633-X