Cycloaddition Reactions of Azides Including Bioconjugation

作者: S. Bräse , A. Friedrich , M. Gartner , T. Schröder

DOI: 10.1007/7081_2007_104

关键词:

摘要: Organic azides R-N3, albeit being energy-rich and very reactive, are useful intermediates in organic synthesis. The cycloaddition reaction of with double triple bonds to yield heterocyclic structures – discovered many centuries ago has been evolved into a powerful tool synthesis, material sciences life sciences, thus covered this review. In particular, the recent development catalytic therefore mild conditions led an enormous increase systematic investigation novel applications.

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