Unsupported copper nanoparticles in the 1,3-dipolar cycloaddition of terminal alkynes and azides
作者： Francisco Alonso , Yanina Moglie , Gabriel Radivoy , Miguel Yus
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摘要: Readily prepared copper nanoparticles were found to catalyse the 1,3-dipolar cycloaddition of azides and alkynes up rates comparable those microwave chemistry. Both preparation click reaction are carried out under mild conditions, in short times absence any stabilising additive or ligand. A variety 1,2,3-triazoles excellent yields. mechanism was postulated on basis different reactivity studies deuteration experiments. Copper(I) acetylides demonstrated be real intermediate species.
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