A DNA glycosylase for oxidized thymine residues in Drosophilamelanogaster
作者： Lars H. Breimer
DOI: 10.1016/0006-291X(86)90547-4
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摘要: Abstract A DNA glycosylase activity which excises fragmented thymine residues has been identified in cell extracts from Drosophila melanogaster embryos. The enzyme an apparent M r = 40,000, acts preferentially on double-stranded polydeoxyribonucleotide substrate and requires no co-factors. presumably excision-repair of pyrimidines damaged by hydroxyl radicals other oxidizing species. This is the first identification a cells.
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