Varicella-zoster virus as a live recombinant vaccine
作者： Edward M. Scolnick , Robert S. Lowe , Ronald W. Ellis , Elliott Kieff
DOI:
关键词:
摘要: A vaccine strain of varicella-zoster virus (VZV), tested in clinical trials, is capable preventing chickenpox children. This has been modified by the introduction into its genome heterologous DNA which encodes an immunogenic polypeptide another human pathogen. expressed cells infected recombinant virus. Such VZV useful as a for well pathogens.
lens.org 参考文章(11)
Malon Kit, Saul Kit, Thymidine kinase negative insertion mutants of pseudorabies virus and methods for the production of same ,(1986)
A.J. Davison, DNA sequence of the US component of the varicella-zoster virus genome. The EMBO Journal. ,vol. 2, pp. 2203- 2209 ,(1983) , 10.1002/J.1460-2075.1983.TB01724.X
Russell John Mccandliss, David M. Anderson, Cloned gene and method for making and using the same. ,(1985)
Leonard E. Post, Bernard Roizman, Recombinant method and materials ,(1982)
Renato Dulbecco, Viruses with recombinant surface proteins. ,(1983)
E. Paoletti, B. R. Lipinskas, C. Samsonoff, S. Mercer, D. Panicali, Construction of live vaccines using genetically engineered poxviruses: biological activity of vaccinia virus recombinants expressing the hepatitis B virus surface antigen and the herpes simplex virus glycoprotein D Proceedings of the National Academy of Sciences of the United States of America. ,vol. 81, pp. 193- 197 ,(1984) , 10.1073/PNAS.81.1.193
David Cavanagh, Viral and bacterial vectors of immunogenes Vaccine. ,vol. 3, pp. 45- 48 ,(1985) , 10.1016/0264-410X(85)90011-8
Bernard Roizman, Herpes simplex virus as a vector ,(1985)
M. Mackett, G. L. Smith, Vaccinia Virus Expression Vectors Journal of General Virology. ,vol. 67, pp. 2067- 2082 ,(1986) , 10.1099/0022-1317-67-10-2067
Bernard Roizman, Leonard E. Post, Recombinant methods and materials ,(1985)