Copper-Mediated Coupling of 1,1-Dibromo-1-alkenes with Nitrogen Nucleophiles: A General Method for the Synthesis of Ynamides
作者： Alexis Coste , Ganesan Karthikeyan , François Couty , Gwilherm Evano
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摘要: Mild reaction conditions are the advantage of title reaction, which allows straightforward entry to a variety ynamides starting from readily available 1,1-dibromo-1-alkenes, act as attractive alkynylating agents (see scheme; EWG = electron-withdrawing group, DMF N,N-dimethylformamide).
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