Process for the fermentative production of heterologous proteins by means of Escherichia coli

作者: Günter Dr. Wich , Tobias Dr. Dassler , Simone Dr. Mitterweger

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摘要: Producing a heterologous protein, comprises cultivating Escherichia coli strain in fermentation medium, and separating the protein from where E. contains gene encoding is functionally linked with signal sequence peptide, releases into medium exhibits an attenuated guanosine tetraphosphate (ppGpp)/guanosine pentaphosphate (pppGpp)-synthetase II activity (PSII activity).

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