Liquid–liquid extraction combined with differential isotope dimethylaminophenacyl labeling for improved metabolomic profiling of organic acids

作者: Jun Peng , Liang Li

DOI: 10.1016/J.ACA.2013.07.045

关键词:

摘要: A large fraction of the known human metabolome belong to organic acids. However, comprehensive profiling of the organic acid sub-metabolome is a major analytical challenge. In this …

参考文章(25)
Patricia M. Jones, Michael J. Bennett, Urine organic acid analysis for inherited metabolic disease using gas chromatography-mass spectrometry. Methods of Molecular Biology. ,vol. 603, pp. 423- 431 ,(2010) , 10.1007/978-1-60761-459-3_41
P Duez, A Kumps, Y Mardens, GC-MS profiling of urinary organic acids evaluated as a quantitative method. Clinical Chemistry. ,vol. 42, pp. 1609- 1615 ,(1996) , 10.1093/CLINCHEM/42.10.1609
H.M. Liebich, Sample preparation for organic acids in biological fluids Analytica Chimica Acta. ,vol. 236, pp. 121- 130 ,(1990) , 10.1016/S0003-2670(00)83305-X
Pornswan Wasant, Somporn Liammongkolkul, Chulaluck Kuptanon, Nithiwat Vatanavicharn, Achara Sathienkijakanchai, Toshihiro Shinka, Organic acid disorders detected by urine organic acid analysis: Twelve cases in Thailand over three-year experience Clinica Chimica Acta. ,vol. 392, pp. 63- 68 ,(2008) , 10.1016/J.CCA.2008.02.015
Jenny M. Armenta, Diego F. Cortes, John M. Pisciotta, Joel L. Shuman, Kenneth Blakeslee, Dominique Rasoloson, Oluwatosin Ogunbiyi, David J. Sullivan, Vladimir Shulaev, Sensitive and rapid method for amino acid quantitation in malaria biological samples using AccQ.Tag ultra performance liquid chromatography-electrospray ionization-MS/MS with multiple reaction monitoring. Analytical Chemistry. ,vol. 82, pp. 548- 558 ,(2010) , 10.1021/AC901790Q