Feed or food responsible for the presence of low-level thiouracil in urine of livestock and humans?
作者： Julie Vanden Bussche , Julie A. L. Kiebooms , Nathalie De Clercq , Yoann Deceuninck , Bruno Le Bizec
DOI: 10.1021/JF200556X
关键词:
摘要: In recent years, questions have been raised on the possible semi-endogenous status of alleged xenobiotic thyreostatic drug thiouracil; thiouracil has detected in urine various animals (livestock and domesticated) at concentrations between 1 10 μg L–1 also human urine. Although several studies suggest Brassicaceae-derived feed as potential origin, no traces so far. Therefore, aim this study was to elucidate origin livestock humans. To purpose Brassicaceae food sources (e.g., rapeseed, rapeseed coarse meal, cabbage, cauliflower, broccoli) were investigated for presence thiouracil. addition, impact Brassicaceae-related β-thioglucosidase enzyme evaluated. This myrosinase appeared be crucial, because without its catalyzed hydrolysis could samples. a sample pretreatment wi...
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