Function of DNA Polymerase III in DNA Replication

作者: VOLKER NÜSSLEIN , BERND OTTO , FRIEDRICH BONHOEFFER , HEINZ SCHALLER

DOI: 10.1038/NEWBIO234285A0

关键词:

摘要: RECENTLY an in vitro system for DNA replication has been described. This could be divided into two fractions (A and B) both of which are necessary proper replication1. Fraction A, the “soluble” fraction, contains those proteins do not tightly bind to membranes or native DNA. B, “insoluble” consists membranous structures bound either them. It was shown that soluble fraction at least one component is needed about vivo concentration1. Studies such described following.

参考文章(1)
T. Kornberg, M. L. Gefter, Purification and DNA Synthesis in Cell-Free Extracts: Properties of DNA Polymerase II Proceedings of the National Academy of Sciences of the United States of America. ,vol. 68, pp. 761- 764 ,(1971) , 10.1073/PNAS.68.4.761