First and second dose antibody responses to pneumococcal polysaccharide vaccine in infants.

摘要: Total (radioimmunoassay) and immunoglobulin class-specific (enzyme-linked immunosorbent assay) antibody responses to pneumococcal capsular polysaccharides were measured in children who received the first dose of 14-valent or control (saline) vaccine at age 7 months second 13 months. Types 3 18C elicited strong types 14 19F intermediate all classes after both doses vaccine. The generally poor immunogen 6A 23F a weak response mainly M class. levels most also decreased rapidly injections