Orientation of Turing-like Patterns by Morphogen Gradients and Tissue Anisotropies

摘要: Patterning of periodic stripes during development requires mechanisms to control both stripe spacing and orientation. A number models can explain how is controlled, including molecular mechanisms, such as Turing's reaction-diffusion model, well cell-based mechanical mechanisms. However, orientation controlled in each these cases poorly understood. Here, we model using a simple, yet generic patterning, with the aim finding qualitative features that are mechanism-independent. Our predicts three qualitatively distinct classes mechanism: gradients production rates, parameters, anisotropies (e.g. diffusion or growth). We provide evidence results from our minimal may also apply more specific complex models, revealing be common variety biological systems.