Trace elements and cancer risk: a review of the epidemiologic evidence

摘要: Worldwide, there are more than 10 million new cancer cases each year, and is the cause of approximately 12% all deaths. Given this, a large number epidemiologic studies have been undertaken to identify potential risk factors for cancer, amongst which association with trace elements has received considerable attention. Trace elements, such as selenium, zinc, arsenic, cadmium, nickel, found naturally in environment, human exposure derives from variety sources, including air, drinking water, food. particular interest given that levels them potentially modifiable. In this review, we focus largely on between noted above cancers lung, breast, colorectum, prostate, urinary bladder, stomach. Overall, evidence currently available appears support an inverse selenium prostate risk, possibly also reduction respect lung although additional prospective needed. There limited zinc breast again, needed confirm this. Most reported no colorectal, stomach risk. compelling positive associations arsenic both bladder cancers, cadmium