摘要: Epithelial injury is a critical event in the development of acute lung injury, but mechanisms that cause death alveolar epithelium are not completely understood. occurs by necrosis and apoptosis; more information needed about balance between these two types cell lungs. Direct epithelial probably response to bacterial exotoxins overdistension units mechanical ventilation. Apoptosis regulated form mediated membrane receptors direct mitochondrial injury. pathways activated lungs patients with part activation Fas receptor soluble ligand (sFasL), which accumulates biologically active at onset Accumulating evidence humans experimental models links sFasL pathway fibrosis. New strategies inhibit Fas-mediated apoptosis need be developed order develop new ways preserve function who
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