An update on the role of opioids in the management of chronic pain of nonmalignant origin.
作者： Jette Højsted , Per Sjøgren
DOI: 10.1097/ACO.0B013E3282EF6B18
关键词:
摘要: PURPOSE OF REVIEW To summarize and reflect over primarily recent epidemiological randomized controlled trials in opioid-treated chronic nonmalignant pain patients, focusing on effects, side risks long-term consequences of the treatment. RECENT FINDINGS In western world opioids are increasingly being used for treatment pain. While benefits regarding relief, functional capacity health-related quality life still remain to be proven, studies emerging that describe serious such as addiction, opioid-induced hyperalgesia, cognitive disorders, suppression immune reproductive systems. SUMMARY Much more research is needed concerning long-time effects opioid therapy patients; however, some clear warning signals have been sent out within years.
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