Crossreactivity of antiphospholipid antibodies.

摘要: Using a solid phase radioimmunoassay to detect anticardiolipin antibodies, the crossreactivity of these antibodies with phospholipids and DNA was tested in 10 patients autoimmune disorders 1 patient secondary syphilis. The anti-ds anti-ss cardiolipin additional SLE. In sera high antibody levels, there marked inhibition activity by negatively charged phospholipids. zwitterionic inhibited some sera, instances where this occurred, less than that obtained for There minimal ss only 2 no ds any tested. Conversely, correlation between levels either or levels. These results suggest antiphospholipid anti-DNA are largely separate groups antibodies. On basis studies, we may be various SLE other disorders.