Highly active thermomorphic fluorous palladacycle catalyst precursors for the Heck reaction; evidence for a palladium nanoparticle pathway.
作者： Christian Rocaboy , J. A. Gladysz
DOI: 10.1021/OL025790R
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摘要: The fluorous Schiff base p-Rf8(CH2)3C6H4C(N(CH2)3Rf8)(CH2)2Rf8 (Rf8 = n-C8F17) is prepared in six steps from p-iodobenzaldehyde and then cyclopalladated (Pd(OAc)2) to give highly effective catalyst precursors for Heck reactions, conducted under homogeneous conditions (DMF, 80−140 °C, turnover numbers >106) the absence of solvents. Rate, recycling, other data suggest that palladacycles serve as sources palladium nanoparticles, which are dominant active catalysts.
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