Nanoparticles and the skin – applications and limitations
作者： Majella E. Lane
DOI: 10.3109/02652048.2011.599440
关键词:
摘要: In recent years, nanotechnology and nanoengineering have stimulated much research in the field of drug delivery. This review examines different types non-deformable nanoparticles (NP) which been developed for pharmaceutical applications. Metal, metallic oxide, polymeric, starch, quantum dot, fullerene carbon nanotube NP are discussed. Only those studies focused on particle interaction with human porcine skin models vitro vivo considered. Particular emphasis is given to disposition transfer skin. As methodology experimental design published should an impact results obtained, these also critically examined.
informahealthcare.com参考文章(48)
Kenneth A. Walters, Dermatological And Transdermal Formulations ,(2002)
Xiao Wu, Gareth J. Price, Richard H. Guy, Disposition of nanoparticles and an associated lipophilic permeant following topical application to the skin. Molecular Pharmaceutics. ,vol. 6, pp. 1441- 1448 ,(2009) , 10.1021/MP9001188
Xin R. Xia, Nancy A. Monteiro-Riviere, Jim E. Riviere, Skin penetration and kinetics of pristine fullerenes (C60) topically exposed in industrial organic solvents Toxicology and Applied Pharmacology. ,vol. 242, pp. 29- 37 ,(2010) , 10.1016/J.TAAP.2009.09.011
B.W. Barry, Lipid-Protein-Partitioning theory of skin penetration enhancement Journal of Controlled Release. ,vol. 15, pp. 237- 248 ,(1991) , 10.1016/0168-3659(91)90115-T
Annika Vogt, Behazine Combadiere, Sabrina Hadam, Karola M. Stieler, Juergen Lademann, Hans Schaefer, Brigitte Autran, Wolfram Sterry, Ulrike Blume-Peytavi, 40 nm, but not 750 or 1,500 nm, Nanoparticles Enter Epidermal CD1a+ Cells after Transcutaneous Application on Human Skin Journal of Investigative Dermatology. ,vol. 126, pp. 1316- 1322 ,(2006) , 10.1038/SJ.JID.5700226
A.O. Gamer, E. Leibold, B. van Ravenzwaay, The in vitro absorption of microfine zinc oxide and titanium dioxide through porcine skin. Toxicology in Vitro. ,vol. 20, pp. 301- 307 ,(2006) , 10.1016/J.TIV.2005.08.008
Fiorenza Rancan, Dimitrios Papakostas, Sabrina Hadam, Steffen Hackbarth, Thierry Delair, Charlotte Primard, Bernard Verrier, Wolfram Sterry, Ulrike Blume-Peytavi, Annika Vogt, Investigation of Polylactic Acid (PLA) Nanoparticles as Drug Delivery Systems for Local Dermatotherapy Pharmaceutical Research. ,vol. 26, pp. 2027- 2036 ,(2009) , 10.1007/S11095-009-9919-X
Mark A. Mitchnick, David Fairhurst, Sheldon R. Pinnell, Microfine zinc oxide (Z-Cote) as a photostable UVA/UVB sunblock agent Journal of The American Academy of Dermatology. ,vol. 40, pp. 85- 90 ,(1999) , 10.1016/S0190-9622(99)70532-3
Jianhong Wu, Wei Liu, Chenbing Xue, Shunchang Zhou, Fengli Lan, Lei Bi, Huibi Xu, Xiangliang Yang, Fan-Dian Zeng, Toxicity and penetration of TiO2 nanoparticles in hairless mice and porcine skin after subchronic dermal exposure. Toxicology Letters. ,vol. 191, pp. 1- 8 ,(2009) , 10.1016/J.TOXLET.2009.05.020
X. Wu, K. Landfester, A. Musyanovych, R.H. Guy, Disposition of Charged Nanoparticles after Their Topical Application to the Skin Skin Pharmacology and Physiology. ,vol. 23, pp. 117- 123 ,(2010) , 10.1159/000270381