摘要: Sarcoidosis is a systemic inflammatory granulomatous disease for which rheumatologists are uniquely trained and qualified to treat. Historically, sarcoidosis has been managed within silos of medical subspecialties, but with increased appreciation the nature this disorder availability more therapeutic options, it clear that multidisciplinary approach, rheumatologist as key component, can offer optimal care. This manuscript reviews clinically relevant immunology pathophysiology, diagnostic issues, management decision-making, therapeutics in care patients sarcoidosis. Issues particularly highlighted. These include aiding establishing diagnosis; recognition manifestations involving bone, joint, muscle; calcium metabolism metabolic bone disease; formulation implementation anti-inflammatory immunomodulatory therapies.