The epidemiology of primary dystonia: current evidence and perspectives.

摘要: The number of existing cases primary dystonia in the population is not precisely known, but condition probably much more frequent than reported. By minimum prevalence estimates, should be considered third most movement disorders after essential tremor and Parkinson's disease. likely etiologic scenario suggested by epidemiological data that dystonias are products a genetic background an environmental insult. Current information on causation dystonia, late-onset particular, often unreliable because methodological problems inherent to case-control investigation heterogeneity dystonia. To expand our knowledge we need design population-based studies, perform association studies taking into account collect exhaustive clinical standardized reliable way.