Understanding microRNAs regulation in heat shock response in the sea cucumber Apostichopus japonicus.
作者： Chao Li , Dongxue Xu
DOI: 10.1016/J.FSI.2018.07.034
关键词:
摘要: Abstract The sea cucumber Apostichopus japonicus is a valuable species in China. extreme high temperature the summer often results mortality. MicroRNAs (miRNAs) play important post-transcriptional regulatory roles gene expression and can influence heat shock response (HSR) greatly. In this study, we determined profiles of miRNAs under stress (HS) A. by using high-throughput sequencing technique. Among differential miRNAs, highlighted 41 differentially expressed many which were involved immunity process disease regulation. Gene ontology pathway analyses putative target genes also carried out. Cell-substrate adherens junction cell-substrate significantly enriched GO analysis. Moreover, made correlation analysis between remarkable (DEGs) cucumbers HS. We identified 17 key miRNA-target pairs potentially regulated HSR cucumbers. These will provide new insights about regulation molecular adaptive mechanisms
sci-hub.se 参考文章(49)
Pier Morin, Kenneth B. Storey, Cloning and expression of hypoxia-inducible factor 1α from the hibernating ground squirrel, Spermophilus tridecemlineatus Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. ,vol. 1729, pp. 32- 40 ,(2005) , 10.1016/J.BBAEXP.2005.02.009
Tiziano Verri, Genciana Terova, Alessandro Romano, Amilcare Barca, Paola Pisani, Carlo Storelli, Marco Saroglia, The SoLute Carrier (SLC) Family Series in Teleost Fish Wiley‐Blackwell. pp. 219- 320 ,(2012) , 10.1002/9781118350041.CH10
Dongxue Xu, Lina Sun, Shilin Liu, Libin Zhang, Xiaoshang Ru, Ye Zhao, Hongsheng Yang, Molecular cloning of heat shock protein 10 (Hsp10) and 60 (Hsp60) cDNAs and their expression analysis under thermal stress in the sea cucumber Apostichopus japonicus Comparative Biochemistry and Physiology B. ,vol. 171, pp. 49- 57 ,(2014) , 10.1016/J.CBPB.2014.03.009
Ramesh A. Shivdasani, MicroRNAs : regulators of gene expression and cell differentiation Blood. ,vol. 108, pp. 3646- 3653 ,(2006) , 10.1182/BLOOD-2006-01-030015
Pengjuan Zhang, Chenghua Li, Yina Shao, Xiaochong Chen, Ye Li, Xiurong Su, Taiwu Li, Identification and characterization of miR-92a and its targets modulating Vibrio splendidus challenged Apostichopus japonicus. Fish & Shellfish Immunology. ,vol. 38, pp. 383- 388 ,(2014) , 10.1016/J.FSI.2014.04.007
Pengjuan Zhang, Chenghua Li, Lin Zhu, Xiurong Su, Ye Li, Chunhua Jin, Taiwu Li, De novo assembly of the sea cucumber Apostichopus japonicus hemocytes transcriptome to identify miRNA targets associated with skin ulceration syndrome. PLOS ONE. ,vol. 8, ,(2013) , 10.1371/JOURNAL.PONE.0073506
R Roufayel, D S Johnston, D D Mosser, The elimination of miR-23a in heat-stressed cells promotes NOXA-induced cell death and is prevented by HSP70 Cell Death and Disease. ,vol. 5, ,(2014) , 10.1038/CDDIS.2014.484
Paul A. Tambyah, Sugunavathi Sepramaniam, Jaminah Mohamed Ali, Siaw Ching Chai, Priyadharshini Swaminathan, Arunmozhiarasi Armugam, Kandiah Jeyaseelan, microRNAs in Circulation Are Altered in Response to Influenza A Virus Infection in Humans PLoS ONE. ,vol. 8, pp. e76811- 11 ,(2013) , 10.1371/JOURNAL.PONE.0076811
Huan Zhao, Hongsheng Yang, Heling Zhao, Muyan Chen, Tianming Wang, The molecular characterization and expression of heat shock protein 90 (Hsp90) and 26 (Hsp26) cDNAs in sea cucumber (Apostichopus japonicus) Cell Stress & Chaperones. ,vol. 16, pp. 481- 493 ,(2011) , 10.1007/S12192-011-0260-Z
Ao-Lin Hsu, Coleen T Murphy, Cynthia Kenyon, Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor Science. ,vol. 300, pp. 1142- 1145 ,(2003) , 10.1126/SCIENCE.1083701