STUDIES ON BLOOD-BRAIN BARRIER WITH RADIOACTIVE PHOSPHORUS

作者: LOUIS BAKAY

DOI: 10.1001/ARCHNEURPSYC.1953.02320310036002

关键词:

摘要: SHORTLY after the discovery was made that central nervous system cannot be stained by intravenous injection of vital dyes and concept a blood-brain barrier established, question arose: Does or does not this exist at birth? The phenomenon kernicterus seemed to indicate in newborn infant is yet fully developed, experiments with young animals gave some support inference. evidence these offered certain, however. Moreover, early investigations yielded contradictory results. It thought application radioactive phosphate would clarify matter development blood-barrier also reveal whether similarity exists, intrauterine postnatal stage, permeability pigments (bilirubin), dyes, ions (P32). analogy between response

参考文章(11)
B.A. Fries, I.L. Chaikoff, The phosphorus metabolism of the brain as measured with radioactive phosphorus. Journal of Biological Chemistry. ,vol. 141, pp. 479- 485 ,(1941) , 10.1016/S0021-9258(18)72793-2
L.B. Flexner, D.B. Cowie, L.M. Hellman, W.S. Wilde, G.J. Vosburgh, The permeability of the human placenta to sodium in normal and abnormal pregnancies and the supply of sodium to the human fetus as determined with radioactive sodium. American Journal of Obstetrics and Gynecology. ,vol. 55, pp. 469- 480 ,(1948) , 10.1016/S0002-9378(15)32966-5
L.M. Hellman, L.B. Flexner, W.S. Wilde, G.J. Vosburgh, N.K. Proctor, The permeability of the human placenta to water and the supply of water to the human fetus as determined with deuterium oxide American Journal of Obstetrics and Gynecology. ,vol. 56, pp. 861- 868 ,(1948) , 10.1016/0002-9378(48)90444-X
Louis B. Flexner, Alfred Gellhorn, The comparative physiology of placental transfer American Journal of Obstetrics and Gynecology. ,vol. 43, pp. 965- 974 ,(1942) , 10.1016/S0002-9378(42)91018-4
Harland W. Mossman, The rabbit placenta and the problem of placental transmission American Journal of Anatomy. ,vol. 37, pp. 433- 497 ,(1926) , 10.1002/AJA.1000370303
LOUIS BAKAY, STUDIES ON BLOOD-BRAIN BARRIER WITH RADIOACTIVE PHOSPHORUS A.M.A. Archives of Neurology & Psychiatry. ,vol. 68, pp. 629- 640 ,(1952) , 10.1001/ARCHNEURPSYC.1952.02320230055006
LOUIS BAKAY, STUDIES ON THE BLOOD-BRAIN BARRIER WITH RADIOACTIVE PHOSPHORUS Archives of Neurology And Psychiatry. ,vol. 66, pp. 419- 426 ,(1951) , 10.1001/ARCHNEURPSYC.1951.02320100019003
Walter S. Wilde, Dean B. Cowie, Louis B. Flexner, Permeability of the placenta of the guinea pig to inorganic phosphate and its relation to fetal growth. American Journal of Physiology. ,vol. 147, pp. 360- 369 ,(1946) , 10.1152/AJPLEGACY.1946.147.2.360