Neurobiology meets genomic science: the promise of human-induced pluripotent stem cells.
作者： Hanna E. Stevens , Jessica Mariani , Gianfilippo Coppola , Flora M. Vaccarino
DOI: 10.1017/S095457941200082X
关键词:
摘要: The recent introduction of the induced pluripotent stem cell technology has made possible derivation neuronal cells from somatic obtained human individuals. This in turn opened new areas investigation that can potentially bridge gap between neuroscience and psychopathology. For first time we study biology genetics neurons derived any individual. Furthermore, by recapitulating vitro developmental steps whereby give rise to cells, now hope understand factors control typical atypical development. We begin explore how genes their variants are transcribed into messenger RNAs within developing these gene transcripts cells. Thus, human-induced have potential uncover not only what aspects development uniquely but also variations series events necessary for normal brain predispose
sci-hub.se 参考文章(101)
Arturo Alvarez-Buylla, Daniel G. Herrera, Hynek Wichterle, The subventricular zone: source of neuronal precursors for brain repair. Progress in Brain Research. ,vol. 127, pp. 1- 11 ,(2000) , 10.1016/S0079-6123(00)27002-7
Flora M. Vaccarino, Alexander Eckehart Urban, Hanna E. Stevens, Anna Szekely, Alexej Abyzov, Elena L. Grigorenko, Mark Gerstein, Sherman Weissman, Annual Research Review: The promise of stem cell research for neuropsychiatric disorders Journal of Child Psychology and Psychiatry. ,vol. 52, pp. 504- 516 ,(2011) , 10.1111/J.1469-7610.2010.02348.X
Zhi Gang Xue, Nicole M. Le Douarin, Julian Smith, Insulin and insulin-like growth factor-I can trigger the differentiation of catecholaminergic precursors in cultures of dorsal root ganglia Cell Differentiation and Development. ,vol. 25, pp. 1- 10 ,(1988) , 10.1016/0922-3371(88)90050-0
Erika Pedrosa, Vladislav Sandler, Abhishek Shah, Reed Carroll, Chanjung Chang, Shira Rockowitz, Xingyi Guo, Deyou Zheng, Herbert M. Lachman, Development of patient-specific neurons in schizophrenia using induced pluripotent stem cells. Journal of Neurogenetics. ,vol. 25, pp. 88- 103 ,(2011) , 10.3109/01677063.2011.597908
B. G. Rash, H. D. Lim, J. J. Breunig, F. M. Vaccarino, FGF Signaling Expands Embryonic Cortical Surface Area by Regulating Notch-Dependent Neurogenesis The Journal of Neuroscience. ,vol. 31, pp. 15604- 15617 ,(2011) , 10.1523/JNEUROSCI.4439-11.2011
Chindo Hicks, Rozana Asfour, Antonio Pannuti, Lucio Miele, An Integrative Genomics Approach to Biomarker Discovery in Breast Cancer Cancer Informatics. ,vol. 10, pp. 185- 204 ,(2011) , 10.4137/CIN.S6837
Arnold Kriegstein, Stephen Noctor, Verónica Martínez-Cerdeño, Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion Nature Reviews Neuroscience. ,vol. 7, pp. 883- 890 ,(2006) , 10.1038/NRN2008
Ana Milosevic, Stephen C. Noctor, Veronica Martinez-Cerdeno, Arnold R. Kriegstein, James E. Goldman, Progenitors from the postnatal forebrain subventricular zone differentiate into cerebellar-like interneurons and cerebellar-specific astrocytes upon transplantation. Molecular and Cellular Neuroscience. ,vol. 39, pp. 324- 334 ,(2008) , 10.1016/J.MCN.2008.07.015
S. J. M. C. Palmen, H. van Engeland, Review on structural neuroimaging findings in autism. Journal of Neural Transmission. ,vol. 111, pp. 903- 929 ,(2004) , 10.1007/S00702-003-0068-9
Trond Aasen, Angel Raya, Maria J Barrero, Elena Garreta, Antonella Consiglio, Federico Gonzalez, Rita Vassena, Josipa Bilić, Vladimir Pekarik, Gustavo Tiscornia, Michael Edel, Stéphanie Boué, Juan Carlos Izpisúa Belmonte, Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nature Biotechnology. ,vol. 26, pp. 1276- 1284 ,(2008) , 10.1038/NBT.1503