Early ERF Responses to Final Words in a Sentence Context during Reading in Individuals with Autism Spectrum Disorders: An MEG Study

摘要: This study used magnetoencephalography (MEG) to the neural basis of abnormalities in sentence context effects individuals with an autism spectrum disorder (ASD) and typically developing (TD) individuals. Early ERF responses (~150ms) three different types final words [dominant homonyms (DH), subordinate (SH), unambiguous (UW)] were analyzed. In both participant groups, strong observed at word response latency over left-occipito mid-parietal regions. There no significant differences between groups any 150ms. The responses, however, significantly modulated by category within groups. TD, UW was than DH SH predominantly left hemisphere. conditions TD On other hand, ASD, there a difference each paired condition, where mainly right These results are consistent argument that early semantic access takes place as 150ms after onset word. Moreover, these findings suggest atypical representations for more less frequent meanings ASD.