Developmental Function in Toddlers With Sickle Cell Anemia
作者： F. D. Armstrong , T. D. Elkin , R. C. Brown , P. Glass , S. Rana
关键词:
摘要: BACKGROUND: Neurocognitive impairment occurs in children and adults with sickle cell anemia, but little is known about neurodevelopment very young children. We examined the neurodevelopmental status of infants participating Pediatric Hydroxyurea Phase III Clinical Trial (Baby Hug) to determine relationships age, cerebral blood flow velocity, hemoglobin concentration. METHODS: Standardized measures infant were administered 193 SS or S-β 0 thalassemia between 7 18 months age at time their baseline evaluation. Associations scores family income, parent education, concentration, transcranial Doppler velocity examined. RESULTS: Mean functioning on scales was average range. There no mental development CONCLUSIONS: Whereas overall normal range, behavioral adaptive function poorer older even this group Explanatory mechanisms for association developmental need be identified.
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