Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection

作者: David Favre , Sharon Lederer , Bittoo Kanwar , Zhong-Min Ma , Sean Proll

DOI: 10.1371/JOURNAL.PPAT.1000295

关键词:

摘要: Chronic immune activation and progression to AIDS are observed after SIV infection in macaques but not in natural host primate species. To better understand this dichotomy, we …

参考文章(70)
Suzanne R. Broussard, Silvija I. Staprans, Robert White, Evelyn M. Whitehead, Mark B. Feinberg, Jonathan S. Allan, Simian Immunodeficiency Virus Replicates to High Levels in Naturally Infected African Green Monkeys without Inducing Immunologic or Neurologic Disease Journal of Virology. ,vol. 75, pp. 2262- 2275 ,(2001) , 10.1128/JVI.75.5.2262-2275.2001
Zvi Grossman, Martin Meier-Schellersheim, Ana E. Sousa, Rui M.M. Victorino, William E. Paul, CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause? Nature Medicine. ,vol. 8, pp. 319- 323 ,(2002) , 10.1038/NM0402-319
Jonathan L Heeney, Angus G Dalgleish, Robin A Weiss, Origins of HIV and the evolution of resistance to AIDS. Science. ,vol. 313, pp. 462- 466 ,(2006) , 10.1126/SCIENCE.1123016
Xiao Chen, Sanja Vodanovic-Jankovic, Bryon Johnson, Melissa Keller, Richard Komorowski, William R. Drobyski, Absence of regulatory T cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft versus host disease Blood. ,vol. 110, pp. 3804- 3813 ,(2007) , 10.1182/BLOOD-2007-05-091074
Adriano Boasso, Jean-Philippe Herbeuval, Andrew W. Hardy, Stephanie A. Anderson, Matthew J. Dolan, Dietmar Fuchs, Gene M. Shearer, HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells. Blood. ,vol. 109, pp. 3351- 3359 ,(2007) , 10.1182/BLOOD-2006-07-034785
Joseph M. McCune, The dynamics of CD4 + T-cell depletion in HIV disease Nature. ,vol. 410, pp. 974- 979 ,(2001) , 10.1038/35073648
Manuela Raffatellu, Renato L Santos, David E Verhoeven, Michael D George, R Paul Wilson, Sebastian E Winter, Ivan Godinez, Sumathi Sankaran, Tatiane A Paixao, Melita A Gordon, Jay K Kolls, Satya Dandekar, Andreas J Bäumler, None, Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut Nature Medicine. ,vol. 14, pp. 421- 428 ,(2008) , 10.1038/NM1743
Janette Furuzawa-Carballeda, María Inés Vargas-Rojas, Antonio R. Cabral, Autoimmune inflammation from the Th17 perspective Autoimmunity Reviews. ,vol. 6, pp. 169- 175 ,(2007) , 10.1016/J.AUTREV.2006.10.002
Guido Silvestri, Mirko Paiardini, Ivona Pandrea, Michael M. Lederman, Donald L. Sodora, Understanding the benign nature of SIV infection in natural hosts Journal of Clinical Investigation. ,vol. 117, pp. 3148- 3154 ,(2007) , 10.1172/JCI33034
Wenjun Ouyang, Jay K. Kolls, Yan Zheng, The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation Immunity. ,vol. 28, pp. 454- 467 ,(2008) , 10.1016/J.IMMUNI.2008.03.004