Lack of Chronic Immune Activation During Natural Host SIV Infection

作者: Vasudha Sundaravaradan , Melanie A. Gasper , Kiran D. Mir , Donald L. Sodora

DOI: 10.1016/B978-0-12-404734-1.00011-5

关键词:

摘要: Simian immunodeficiency virus (SIV)-infected natural hosts do not progress to clinical acquired immune deficiency syndrome yet display high viral replication and an acute immunologic response similar pathogenic SIV/human infections. During chronic SIV infection, suppress their activation, whereas a highly activated state. Here, we review host infections with emphasis on different cell subsets potential roles in suppressing activation during the phase that contributes nonpathogenic outcome of these

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