Tromantadine inhibits a late step in herpes simplex virus type 1 replication and syncytium formation.

作者: Dawn E. Ickes , Tom M. Venetta , Yupa Phonphok , Ken S. Rosenthal

DOI: 10.1016/0166-3542(90)90045-9

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摘要: Abstract Addition of tromantadine after virus penetration inhibited HSV-1 induced syncytium formation and production in HEp-2 VERO cells acted additively with neutralizing antibody blocking spread cytopathology. Inhibition infected 0.01 pfu/cell GC+ was observed at a concentration

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