Morphometry and fluid reabsorption during peristaltic flow in hamster renal papillary collecting ducts

作者: Bodil Schmidt-Nielsen , Larry N. Reinking

DOI: 10.1038/KI.1981.212

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摘要: Morphometry and fluid reabsorption during peristaltic flow in hamster renal papillary collecting ducts. Previously we have shown rodents that when the pelvis is left intact, urine moves as discreet boluses a pulsatile fashion through At low rates, conditions were observed seemed to be unfavorable reabsorption: (1) rapid linear velocity, (2) apparent absence of ducts for long 95% time. The present study used this established data on nature movement duct, plus new morphometric analysis determine rates from hamsters. Total cross sectional areas circumferences duct lumina measured fixed papillae diuretic antidiuretic In addition, diameters vivo determined movies flows. average diameter tissue at various distances tip found similar medullary independent rate. luminal wall area total volume 100-g calculated. last millimeter papilla, surface was 3.13 mm 2 , 23.12 nl. To calculate final ducts, estimated rate 1.0 tip. eight hamsters with an 1.00 ± 0.07 µl·min -1 ·100 g body wt 1.21 0.28 (N = 8). Using above figure hydraulic coefficient 30 nl·cm -2 ·min ·mOsm previously least order magnitude too account Morphometrie et au cours de l'ecoulement peristaltique dans les canaux collecteur medullaires la papille renale du hamster. Nous avons montre anterieurement que chez rongeurs dont le bassinet est intact l'urine s'ecoule papillaires par petits embols d'une facon pulsatile. A debit urinaire faible il ete observe des defavorables une velocite lineaire elevee, l'absence apparente d'urine collecteurs pendant fraction temps allant jusqu'a 95%. Ce travail utilise observations acquises sur mouvement canal papillaire ainsi qu'une analyse morphometrique La al circonference lumiere ont mesurees papilles fixees provenant d'animaux diuretiques non diuretiques. De plus, diametres determines partir cine-enregistrement peristaltique. Le diametre moyen tissus fixes differentes pointe semblable mesure medullaire urinaire. parietale totale d'un 100 calcule. Dans dernier millimetre papille, moyenne 3,13 moyende 23,13 Pour calculer papillaires, evalue travers section 1,0 papille. Chez huit etait 1,00 0,07 poids corporel evaluee 1,21 0,28 L'utilisation ces valeurs pour laminale permet d'indiquer hydraulique d'au moins un ordre grandeur trop rendre compte reabsorption.

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