A dendritic cell multitasks to tackle cancer.
作者： Marianne Burbage , Sebastian Amigorena
DOI: 10.1038/D41586-020-02339-9
关键词:
摘要: Learning how immune cells target tumours is crucial for cancer immunotherapy. The finding that a type of dendritic cell activates two sorts T and coordinates their crosstalk sheds light on responses to tumours. Type 1 activate both CD4 CD8 cells.
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Sarah Eickhoff, Anna Brewitz, Michael Y. Gerner, Frederick Klauschen, Karl Komander, Hiroaki Hemmi, Natalio Garbi, Tsuneyasu Kaisho, Ronald Nathan Germain, Wolfgang Kastenmüller, Robust Anti-viral Immunity Requires Multiple Distinct T Cell-Dendritic Cell Interactions. Cell. ,vol. 162, pp. 1322- 1337 ,(2015) , 10.1016/J.CELL.2015.08.004
Jyh Liang Hor, Paul G. Whitney, Ali Zaid, Andrew G. Brooks, William R. Heath, Scott N. Mueller, Spatiotemporally Distinct Interactions with Dendritic Cell Subsets Facilitates CD4+ and CD8+ T Cell Activation to Localized Viral Infection Immunity. ,vol. 43, pp. 554- 565 ,(2015) , 10.1016/J.IMMUNI.2015.07.020
Miranda L. Broz, Mikhail Binnewies, Bijan Boldajipour, Amanda E. Nelson, Joshua L. Pollack, David J. Erle, Andrea Barczak, Michael D. Rosenblum, Adil Daud, Diane L. Barber, Sebastian Amigorena, Laura J. van’t Veer, Anne I. Sperling, Denise M. Wolf, Matthew F. Krummel, Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity Cancer Cell. ,vol. 26, pp. 638- 652 ,(2014) , 10.1016/J.CCELL.2014.09.007
Martin Guilliams, Florent Ginhoux, Claudia Jakubzick, Shalin H. Naik, Nobuyuki Onai, Barbara U. Schraml, Elodie Segura, Roxane Tussiwand, Simon Yona, Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny Nature Reviews Immunology. ,vol. 14, pp. 571- 578 ,(2014) , 10.1038/NRI3712
Bryan Vander Lugt, Aly A Khan, Jason A Hackney, Smita Agrawal, Justin Lesch, Meijuan Zhou, Wyne P Lee, Summer Park, Min Xu, Jason DeVoss, Chauncey J Spooner, Cecile Chalouni, Lelia Delamarre, Ira Mellman, Harinder Singh, None, Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation Nature Immunology. ,vol. 15, pp. 161- 167 ,(2014) , 10.1038/NI.2795
Giulia Nizzoli, Jana Krietsch, Anja Weick, Svenja Steinfelder, Federica Facciotti, Paola Gruarin, Annalisa Bianco, Bodo Steckel, Monica Moro, Mariacristina Crosti, Chiara Romagnani, Katharina Stölzel, Sara Torretta, Lorenzo Pignataro, Carmen Scheibenbogen, Petra Neddermann, Raffaele De Francesco, Sergio Abrignani, Jens Geginat, Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses. Blood. ,vol. 122, pp. 932- 942 ,(2013) , 10.1182/BLOOD-2013-04-495424
D. Dudziak, A. O. Kamphorst, G. F. Heidkamp, V. R. Buchholz, C. Trumpfheller, S. Yamazaki, C. Cheong, K. Liu, H.-W. Lee, C. G. Park, R. M. Steinman, M. C. Nussenzweig, Differential antigen processing by dendritic cell subsets in vivo Science. ,vol. 315, pp. 107- 111 ,(2007) , 10.1126/SCIENCE.1136080
Elodie Segura, Sebastian Amigorena, Cross-Presentation in Mouse and Human Dendritic Cells. Advances in Immunology. ,vol. 127, pp. 1- 31 ,(2015) , 10.1016/BS.AI.2015.03.002
Paula Michea, Floriane Noël, Eve Zakine, Urszula Czerwinska, Philémon Sirven, Omar Abouzid, Christel Goudot, Alix Scholer-Dahirel, Anne Vincent-Salomon, Fabien Reyal, Sebastian Amigorena, Maude Guillot-Delost, Elodie Segura, Vassili Soumelis, Adjustment of dendritic cells to the breast-cancer microenvironment is subset specific. Nature Immunology. ,vol. 19, pp. 885- 897 ,(2018) , 10.1038/S41590-018-0145-8
Mélanie Durand, Thomas Walter, Tiphène Pirnay, Thomas Naessens, Paul Gueguen, Christel Goudot, Sonia Lameiras, Qing Chang, Nafiseh Talaei, Olga Ornatsky, Tatiana Vassilevskaia, Sylvain Baulande, Sebastian Amigorena, Elodie Segura, Human lymphoid organ cDC2 and macrophages play complementary roles in T follicular helper responses. Journal of Experimental Medicine. ,vol. 216, pp. 1561- 1581 ,(2019) , 10.1084/JEM.20181994