RELEASE INDUCED BY PHENETHYLAMINES

摘要: Publisher Summary This chapter focuses on the release induced by phenethylamines. The neuronal efflux of radioactivity does not represent total because most “free” amine leaves neurone much earlier. Moreover, apparent half time for this late would then reflect net dissociation from extra vesicular binding sites. Both hypothetical models two-compartmental systems that generate a is characterized constant fractional rate loss radioactivity. Phenethylamines are only able to accelerate other phenethylamines but also agents substrates cocaine-sensitive uptake mechanism and accumulated in axoplasm. There evidence indicate bretylium transported into adrenergic nerve ending accelerated amphetamine. However, it an area uncertainty whether saturable when internal sodium concentration normal.