Facile synthesis of amino bicyclo[2.2.1]heptyl alcohol and its application for enantioselective additions of diethylzinc to aldehydes
作者： Naoto Hanyu , Takashi Mino , Masami Sakamoto , Tsutomu Fujita
DOI: 10.1016/S0040-4039(00)00637-7
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摘要: Abstract Enantioselective additions of diethylzinc to aldehydes were demonstrated, and good moderate enantioselectivities (54 95% enantiomeric excess) obtained. The ligand 4 was prepared from camphor acetic acid in a facile process four steps, the chiral source only inexpensive (+)-camphor.
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