The Patterning of Progenitor Tissues for the Cranial Region of the Mouse Embryo During Gastrulation and Early Organogenesis

摘要: Publisher Summary Postimplantation development of the mouse embryo features a series specification events leading to delineation domains tissue progenitors and lineages. Fate mapping studies have shown that there is regionalization cell fate in epiblast at onset gastrulation. In mouse, evidence suggests existence an organizer for body plan during The organization gastrulation early organogenesis depends critically on activity axial structures such as notochord floor plate, which are derived largely from cells node. morphological recognizable node can induce formation supernumerary paraxial host tissues following transplantation heterotopic sites. predecessor presumed be source inductive signal transmitted first planar mode generating anterior-posterior polarity epiblast. mesendoderm this then exert their vertical manner ectoderm juxtaposed morphogenesis.