Bile acid and lysolecithin concentrations in the stomach in patients with duodenal ulcer before operation and after treatment by highly selective vagotomy, partial gastrectomy, or truncal vagotomy and drainage

摘要: Duodenogastric reflux of bile acids and lysolecithin in the course a standard test meal was measured normal people patients with duodenal ulcer before operation more than one year after highly selective vagotomy, Polya partial gastrectomy, truncal vagotomy pyloroplasty, gastrojejunostomy. Before operation, had significantly higher fasting, post-prandial, peak acid concentrations stomach subjects. After were preoperative patients. contrast, lower post-prandial less half (NS) those recorded also gastrojejunostomy; gastrectomy Thus, when used treatment ulcer, keeps `bile' out stomach, probably through its effect on gastric smooth muscle, combined preservation an intact antropyloroduodenal segment. In gastrojejunostomy, pyloroplasty all lead to significant increase into stomach. The clinical importance these findings is that both gastritis and, long term, carcinoma may prove be common or drainage procedure.