Genetic variability in iron-related oxidative stress pathways (Nrf2, NQ01, NOS3, and HO-1), iron intake, and risk of postmenopausal breast cancer.
作者： Chi-Chen Hong , Christine B. Ambrosone , Jiyoung Ahn , Ji-Yeob Choi , Marjorie L. McCullough
DOI: 10.1158/1055-9965.EPI-07-0247
关键词:
摘要: … 2 detoxification genes (33), including NQO1. Oxidative stress promotes nuclear accumulation of Nrf2 and activates transcription of NQO1 and other antioxidant response element–driven …
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