Application of proteomics in non-small-cell lung cancer.

作者: William C S Cho

DOI: 10.1586/14789450.2016.1121813

关键词:

摘要: Non-small-cell lung cancer (NSCLC) is a heterogeneous disease with diverse pathological features. Clinical proteomics allows the discovery of molecular markers and new therapeutic targets for this most prevalent type cancer. Some them may be used to detect early cancer, while others serve as predictive resistance different therapies. Therapeutic prognostic in NSCLC have also been discovered. These biomarkers help pair individual patient best treatment option. Despite fact that implementation these clinic appears scarce, recently launched Precision Medicine Initiative encourage their translation into clinical practice.

参考文章(24)
Heiner Koch, M. Estela Del Castillo Busto, Karl Kramer, Guillaume Médard, Bernhard Kuster, Chemical Proteomics Uncovers EPHA2 as a Mechanism of Acquired Resistance to Small Molecule EGFR Kinase Inhibition Journal of Proteome Research. ,vol. 14, pp. 2617- 2625 ,(2015) , 10.1021/ACS.JPROTEOME.5B00161
Minzhi Zhao, Haiyun Li, Xiangli Bu, Chunni Lei, Qiaojun Fang, Zhiyuan Hu, Quantitative Proteomic Analysis of Cellular Resistance to the Nanoparticle Abraxane ACS Nano. ,vol. 9, pp. 10099- 10112 ,(2015) , 10.1021/ACSNANO.5B03677
Yao Xiao, Jingshu Wang, Yu Qin, Yang Xuan, Yunlu Jia, Wenxian Hu, Wendan Yu, Meng Dai, Zhenglin Li, Canhui Yi, Shilei Zhao, Mei Li, Sha Du, Wei Cheng, Xiangsheng Xiao, Yiming Chen, Taihua Wu, Songshu Meng, Yuhui Yuan, Quentin Liu, Wenlin Huang, Wei Guo, Shusen Wang, Wuguo Deng, Ku80 cooperates with CBP to promote COX-2 expression and tumor growth. Oncotarget. ,vol. 6, pp. 8046- 8061 ,(2015) , 10.18632/ONCOTARGET.3508
Eyra Marien, Michael Meister, Thomas Muley, Steffen Fieuws, Sergio Bordel, Rita Derua, Jeffrey Spraggins, Raf Van de Plas, Jonas Dehairs, Jens Wouters, Muralidhararao Bagadi, Hendrik Dienemann, Michael Thomas, Philipp A. Schnabel, Richard M. Caprioli, Etienne Waelkens, Johannes V. Swinnen, Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles International Journal of Cancer. ,vol. 137, pp. 1539- 1548 ,(2015) , 10.1002/IJC.29517
Michael J. Walker, Cong Zhou, Alison Backen, Maria Pernemalm, Andrew J.K. Williamson, Lynsey J.C. Priest, Pek Koh, Corinne Faivre-Finn, Fiona H. Blackhall, Caroline Dive, Anthony D. Whetton, Discovery and Validation of Predictive Biomarkers of Survival for Non-small Cell Lung Cancer Patients Undergoing Radical Radiotherapy: Two Proteins With Predictive Value EBioMedicine. ,vol. 2, pp. 841- 850 ,(2015) , 10.1016/J.EBIOM.2015.06.013
Shawn J. Rice, Xin Liu, Bruce Miller, Monika Joshi, Junjia Zhu, Carla Caruso, Chris Gilbert, Jennifer Toth, Michael Reed, Negar Rassaei, Arun Das, Amit Barochia, Karam El-Bayoumy, Chandra P. Belani, Proteomic profiling of human plasma identifies apolipoprotein E as being associated with smoking and a marker for squamous metaplasia of the lung. Proteomics. ,vol. 15, pp. 3267- 3277 ,(2015) , 10.1002/PMIC.201500029
Ali Flores‐Pérez, Laurence A Marchat, Lidia López Sánchez, Diana Romero‐Zamora, Elena Arechaga‐Ocampo, Nayeli Ramírez‐Torres, José Díaz Chávez, Ángeles Carlos‐Reyes, Horacio Astudillo‐de la Vega, Erika Ruiz‐García, Abrahan González‐Pérez, César López‐Camarillo, None, Differential proteomic analysis reveals that EGCG inhibits HDGF and activates apoptosis to increase the sensitivity of non-small cells lung cancer to chemotherapy. Proteomics Clinical Applications. ,vol. 10, pp. 172- 182 ,(2016) , 10.1002/PRCA.201500008
Xue-Yan Zhang, Ge Zhang, Ying Jiang, Dan Liu, Man-Zhi Li, Qian Zhong, Shan-Qi Zeng, Wan-Li Liu, Mu-Sheng Zeng, The prognostic value of serum C-reactive protein-bound serum amyloid A in early-stage lung cancer Chinese Journal of Cancer. ,vol. 34, pp. 39- ,(2015) , 10.1186/S40880-015-0039-1
Makoto Kobayashi, Ryo Nagashio, Shi-Xu Jiang, Keita Saito, Benio Tsuchiya, Shinichiro Ryuge, Ken Katono, Hiroyasu Nakashima, Eriko Fukuda, Naoki Goshima, Yukitoshi Satoh, Noriyuki Masuda, Makoto Saegusa, Yuichi Sato, Calnexin is a novel sero-diagnostic marker for lung cancer Lung Cancer. ,vol. 90, pp. 342- 345 ,(2015) , 10.1016/J.LUNGCAN.2015.08.015
W C S Cho, T T Yip, W W Cheng, J S K Au, Serum amyloid A is elevated in the serum of lung cancer patients with poor prognosis. British Journal of Cancer. ,vol. 102, pp. 1731- 1735 ,(2010) , 10.1038/SJ.BJC.6605700