Antisense oligonucleotides against cytochrome P450 2C8 attenuate EDHF-mediated Ca2+ changes and dilation in isolated resistance arteries

作者: Steffen-Sebastian Bolz , Beate Fisslthaler , Susanne Pieperhoff , Cor De Wit , Ingrid Fleming

DOI: 10.1096/FASEBJ.14.2.255

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摘要: Using a novel vessel culture technique in combination with antisense oligonucleotide transfection, we tested whether the endothelium-derived hyperpolarizing factor (EDHF) is cytochrome P450 (CYP)...

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