Circadian Dysfunction and Obesity: Is Leptin the Missing Link?

作者: Charna Dibner , Frédéric Gachon

DOI: 10.1016/J.CMET.2015.08.008

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摘要: While accumulating evidence suggests that circadian desynchrony is linked to obesity and metabolic syndrome, the underlining mechanism still poorly understood. In this issue, Kettner et al. (2015) demonstrate leptin resistance, induced by clock deficiency or chronic jet lag, may represent missing link.

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