The pivotal role of microRNA-155 in the control of cancer.
作者： Zhaolin Chen , Taotao Ma , Cheng Huang , Tingting Hu , Jun Li
DOI: 10.1002/JCP.24492
关键词:
摘要: microRNAs (miRNAs) are emerging as important gene expression regulators linked to various biological processes at a posttranscriptional level. miRNAs have been known play roles in cell proliferation, differentiation, and apoptosis. Recently, accumulate studies indicate that up-regulation of miR-155 has described several types human tumors. considered act an oncogene or tumor suppressor, depending on system. Silencing oncomiRs therapy approaches could be effective therapeutic approach against tumor. Here we review the current knowledge functional role control cancers. J. Cell. Physiol. 229: 545–550, 2014. © 2013 Wiley Periodicals, Inc.
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