Robin sequence: a retrospective review of 115 patients.

摘要: Summary Objectives Review a large series of patients with Robin sequence to document the incidence (1) associated syndromic diagnoses; (2) co-morbid conditions; (3) frequency and type operative management for airway compromise feeding difficulties; (4) possible differences in treatment between nonsyndromic infants. Methods Retrospective case-review 115 managed 1962 2002 at two tertiary-care teaching hospitals evaluation demographic information, clinical findings, interventions. Results Fifty-four percent (N = 63) were nonsyndromic. Syndromic included: Stickler syndrome (18%), velocardiofacial (7%), Treacher-Collins (5%), facial hemifacial microsomia (3%), other defined (3.5%) undefined (9%) disorders. There was no statistical difference regard need (Fisher's exact test, p = 0.264). Forty-two required gastrostomy tube correct difficulties. Patients diagnosis more likely be developmentally delayed. Fifty-one (44%) underwent management: 61% tongue–lip adhesion 39% tracheotomy. Fifteen initially had subsequently While preferred respiratory differed institutions, percentage requiring intervention similar. Conclusions The pathogenesis is multifactorial nearly half patients. Operative failure 44% infants; rate similar both hospitals. approach significantly however, based on philosophy training managing surgical specialty. Co-morbid factors such as baseline cardiopulmonary neurologic status did not play significant role decision making.