Obstructive Sleep Apnea Presenting as Pseudopheochromocytoma: A Case Report

作者: L. J. Hoy , M. Emery , J. A. Wedzicha , A. G. Davison , S. L. Chew

DOI: 10.1210/JC.2003-031348

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摘要: Sudden arousal from sleep causes a transient surge in sympathetic nervous activity. Repeated arousals, as occur obstructive apnea (OSA), are well documented to cause more prolonged overactivity and consequent elevations 24-h urinary catecholamine levels. We describe here series of five patients, each presenting with clinical biochemical picture indistinguishable that pheochromocytoma. Thorough investigations have failed find catecholamine-secreting tumor any these subjects, but all been diagnosed OSA. Primary treatment OSA nasal continuous positive airways pressure has led normalization systemic blood catecholamines. Pseudopheochromocytoma is therefore rare, treatable, presentation apnea.

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