CARCINOMA OF THE CERVIX OF MICE RECEIVING ESTROGENS

摘要: During the past three years hyperplastic epithelial lesions of cervix have been observed following injection estrogens into mice. Recently a carcinoma has obtained which grown transplantation without continuing administration estrogen to host. Several investigators abnormal growths uterine cervices mice estrogens. Loeb, Burns, Suntzeff and Moskop 1 reported precancerous lesion in one mouse. Following application 1: 2: 5: 6-dibenzanthracene, Perry 2 Ginzton 3 Localized infiltrating overgrowths were partially hysterectomized two with intact uteri treatment. 4 or carcinoma-like vagina described. 5 In our laboratory eighteen tumors near