Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6.
作者： Peter L. Toogood , Patricia J. Harvey , Joseph T. Repine , Derek J. Sheehan , Scott N. VanderWel
DOI: 10.1021/JM049354H
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摘要: … Our goal is to identify potent (nanomolar) inhibitors of Cdk4/D that possess sufficient selectivity against other kinases to test the hypothesis that pharmacological inhibition of Cdk4/D will …
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