Dysphagia in children with a 22q11.2 deletion: unusual pattern found on modified barium swallow.

摘要: Abstract Objectives: To delineate feeding dysfunction in a population of children with 22q11.2 deletion and report the associated findings noted during modified barium swallow (MBS). Study design: Seventy-five chromosome history persistent difficulty received evaluation, including an MBS for those whom there was concern about airway penetration. Results: A consistent pattern difficulty, independent palatal or cardiac involvement, emerged from evaluations. This group typically has trouble coordinating suck/swallow/breath pattern, resulting slow nipple feedings interrupted by gagging regurgitation. Recurrent vomiting constipation are common. With advancement to chewable table foods, refusal develops, related immature oral transport pattern. The studies demonstrate pharyngeal hypercontractility, cricopharyngeal prominence, and/or diverticula. Conclusions: Because consistency dysphagic symptoms findings, we propose that dysmotility, especially through pharyngoesophageal segment, is central dysphagia affecting this group. Dysphagia dysmotility may be underdiagnosed erroneously attributed disease. Therefore attention status investigation gastrointestinal as warranted recommended all patients problems. (J Pediatr 2000;137:158-64)