Site-specific recombination between homologous chromosomes in Drosophila

作者: K. Golic

DOI: 10.1126/SCIENCE.2035025

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摘要: The ability to mark a cell and its descendants genetically so that the resulting clone can be distinguished from neighboring cells facilitates studies in animal biology development. A method of generating clones by inducing homologous mitotic recombination Drosophila with site-specific yeast recombinase is described. This allows for frequent mosaicism after exchange induced at predefined sites genome.

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