METHODS AND ASSAYS FOR DISTINGUISHING BETWEEN DIFFERENT FORMS OF DISEASES AND DISORDERS CHARACTERIZED BY THROMBOCYTOPENIA AND/OR BY SPONTANEOUS INTERACTION BETWEEN VON WILLEBRAND FACTOR (vWF) AND PLATELETS

作者: Karen Silence , Rob Fijnheer , Peter J. Lenting , Philip G. de Groot

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摘要: The invention relates to a method for distinguishing between different states or forms of diseases and disorders characterized by thrombocytopenia and/or spontaneous interaction Von Willebrand Factor (vWF) platelets, predict the progression such disease disorder, said comprising steps providing at least one biological sample obtained from patient suffering from, suspected suffer disorder platelets determining amount activated vWF in sample, which is representative disorder. further kit-of-parts use an antibody that capable specifically binding presence non-activated vWF; part fragment antibody.

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